Article
IL-35 recombinant protein reverses inflammatory bowel disease and psoriasis through regulation of inflammatory cytokines and immune cells.
Journal of cellular and molecular medicine - 1 Feb 2018
Wang Yuan, Mao Ying, Zhang Junfeng, Shi Gang, Cheng Lin, Lin Yi, Li Yiming, Zhang Xiaomei, Zhang Yujing, Chen Xiaolei, Deng Jie, Su Xiaolan, Dai Lei, Yang Yang, Zhang Shuang, Yu Dechao, Wei Yuquan, Deng Hongxin
Abstract excerpt
Interleukin-35 (IL-35), a member of the IL-12 family, functions as a new anti-inflammatory factor involved in arthritis, psoriasis, inflammatory bowel disease (IBD) and other immune diseases. Although IL-35 can significantly prevent the development of inflammation in many diseases, there have been no early studies accounting for the role of IL-35 recombinant protein in IBD and psoriasis. In this study, we...
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