Article
Association of IL-35 expression and gene polymorphisms in rheumatoid arthritis.
International immunopharmacology - 1 Jan 2021
Xie Qiang, Xu Wang-Dong, Pan Min, Lan You-Yu, Liu Xiao-Yan, Su Lin-Chong, Huang An-Fang
Abstract excerpt
Interleukin (IL)-35 is the newest member of the IL-12 family. It is expressed in many immune cells and has been recognized as a novel inflammatory cytokine that may have bifunctional properties. Recent findings have indicated that the expression of IL-35 is abnormal in rheumatoid arthritis (RA) patients. However, the results were inconsistent. In this study, 400 RA patients were recruited to evaluate serum levels...
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