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Article

Erythrocyte polyunsaturated fatty acid composition is associated with depression and FADS genotype in Caucasians.

Nutritional neuroscience - 1 Oct 2018

Cribb Lachlan, Murphy Jenifer, Froud Amy, Oliver Georgina, Bousman Chad A, Ng Chee H, Sarris Jerome

Abstract excerpt

BACKGROUND: Polyunsaturated fatty acids (PUFAs) play an important role in the pathophysiology of major depressive disorder (MDD), related, in part, to their role in inflammatory systems. The enzymes δ-5 and δ-6 desaturase are the rate-limiting steps in the metabolism of PUFAs and are encoded in the genes fatty acid desaturase (FADS) 1 and 2, respectively. Single nucleotide polymorphisms (SNPs) and haplotypes...

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Identifiers

PMID: 28552045
DOI: 10.1080/1028415X.2017.1327685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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