Article
PADI4 Polymorphisms in Iranian Patients with Rheumatoid Arthritis.
Acta reumatologica portuguesa - 1 Jan 2000
Shamsian Elmira, Azarian Maryam, Akhlaghi Maassoomeh, Samaei Mehrnoosh, Jamshidi Ahmad Reza, Assar Shirin, Shakiba Yadollah, Gharibdoost Farhad, Nourijelyani Keramat, Mahmoudi Mahdi
Abstract excerpt
AIM: Rheumatoid arthritis (RA) is a chronic autoimmune disease which affects many tissues and organs, but majorly attacks synovial joints. Beyond the major histocompatibility complex (MHC) genes, Peptidyl arginine deiminase type IV (PADI4) has been suggested to be associated with RA susceptibility. Evidence regarding the association of PADI4 single nucleotide polymorphisms (SNP) and RA is controversial, thus we...
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