Article
Regulatory network of GATA3 in pediatric acute lymphoblastic leukemia.
Oncotarget - 30 May 2017
Hou Qianqian, Liao Fei, Zhang Shouyue, Zhang Duyu, Zhang Yan, Zhou Xueyan, Xia Xuyang, Ye Yuanxin, Yang Hanshuo, Li Zhaozhi, Wang Leiming, Wang Xi, Ma Zhigui, Zhu Yiping, Ouyang Liang, Wang Yuelan, Zhang Hui, Yang Li, Xu Heng, Shu Yang
Abstract excerpt
GATA3 polymorphisms were reported to be significantly associated with susceptibility of pediatric B-lineage acute lymphoblastic leukemia (ALL), by impacting on GATA3 expression. We noticed that ALL-related GATA3 polymorphism located around in the tissue-specific enhancer, and significantly associated with GATA3 expression. Although the regulatory network of GATA3 has been well reported in T cells, the functional...
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