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Article

Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease.

Journal of the American Heart Association - 26 May 2017

Song Ci, Burgess Stephen, Eicher John D, O'Donnell Christopher J, Johnson Andrew D

Abstract excerpt

BACKGROUND: Plasminogen activator inhibitor type 1 (PAI-1) plays an essential role in the fibrinolysis system and thrombosis. Population studies have reported that blood PAI-1 levels are associated with increased risk of coronary heart disease (CHD). However, it is unclear whether the association reflects a causal influence of PAI-1 on CHD risk. METHODS AND RESULTS: To evaluate the association between PAI-1 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28550093
DOI: 10.1161/JAHA.116.004918
PMCID: PMC5669150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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