Article
Genetic Variation and Gene Expression Levels of Tight Junction Genes Indicates Relationships Between PTEN as well as MAGI1 and Microscopic Colitis.
Digestive diseases and sciences - 1 Jan 2018
Norén Elisabeth, Mellander Marie-Rose, Almer Sven, Söderman Jan
Abstract excerpt
BACKGROUND AND AIM: Microscopic colitis (MC) has been associated with increased paracellular permeability. Therefore, we aimed to investigate potential associations between MC and several genes encoding tight junction (TJ) proteins reported to interact with each other. METHODS: The association between MC and single nucleotide polymorphisms (SNP; n = 63) within TJ genes (F11R, MAGI1, MAGI2, MAGI3, PARD3, PTEN, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.