Article
Replication of genetic variation in the MYO9B gene in Crohn's disease.
Human immunology - 1 Jul 2011
Wolters Victorien M, Xu Wei, Zhao Xingqiu, Walters Thomas D, Griffiths Anne M, Silverberg Mark S, Muise Aleixo M
Abstract excerpt
Various genes that may influence the intestinal barrier have been identified, including MAGI2, PARD3, and MYO9B. These genes are associated with inflammatory bowel disease (IBD) in several European studies. A total of 2,049 individuals (656 Crohn's disease [CD], 544 ulcerative colitis [UC], and 849 controls) were genotyped and association studies were performed for 1 single nucleotide polymorphism (SNP) in MAGI2,...
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