Article
Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration.
PLoS pathogens - 1 May 2017
González-Motos Víctor, Jürgens Carina, Ritter Birgit, Kropp Kai A, Durán Verónica, Larsen Olav, Binz Anne, Ouwendijk Werner J D, Lenac Rovis Tihana, Jonjic Stipan, Verjans Georges M G M, Sodeik Beate, Krey Thomas, Bauerfeind Rudolf, Schulz Thomas F, Kaufer Benedikt B, Kalinke Ulrich, Proudfoot Amanda E I, Rosenkilde Mette M, Viejo-Borbolla Abel
Abstract excerpt
Varicella zoster virus (VZV) is a highly prevalent human pathogen that establishes latency in neurons of the peripheral nervous system. Primary infection causes varicella whereas reactivation results in zoster, which is often followed by chronic pain in adults. Following infection of epithelial cells in the respiratory tract, VZV spreads within the host by hijacking leukocytes, including T cells, in the tonsils...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.