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Article

A mutation in porcine pre-miR-15b alters the biogenesis of MiR-15b\16-1 cluster and strand selection of MiR-15b.

PloS one - 1 Jan 2017

Sun Wenyang, Lan Jing, Chen Lei, Qiu Jinjie, Luo Zonggang, Li Mingzhou, Wang Jinyong, Zhao Jiugang, Zhang Tinghuan, Long Xi, Chai Jie, Yan Zunqiang, Guo Zongyi, Gun Shuangbao

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs that are involved in translational regulation of the messenger RNA molecules. Sequence variations in the genes encoding miRNAs could influence their biogenesis and function. MiR-15b plays an important role in cellular proliferation, apoptosis and the cell cycle. Here, we report the identification of a C58T mutation in porcine pre-miR-15b. Through in vitro and in vivo...

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Identifiers

PMID: 28542522
DOI: 10.1371/journal.pone.0178045
PMCID: PMC5443575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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