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Article

WNT5B regulates myogenesis and fiber type conversion by affecting mRNA stability.

International journal of biological sciences - 1 Jan 2025

Fan Danyang, Yao Yilong, Yan Chao, Li Fanqinyu, Yang Yalan, Xie Bingkun, Tang Zhonglin

Abstract excerpt

The wingless-integrated (WNT) signaling pathway is known to play a critical role in myogenesis. WNT5B, a member of the WNT family, is essential for determining cell fate and development. However, the molecular mechanisms by which WNT5B regulates myogenesis remain unclear. This study observed that WNT5B, which is conserved between mice and pigs, is highly expressed in the skeletal muscle. The expression of WNT5B...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 40612684
DOI: 10.7150/ijbs.102309
PMCID: PMC12223781

Genes

WNT5B

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