MiR-10a* up-regulates coxsackievirus B3 biosynthesis by targeting the 3D-coding sequence

doi:10.1093/nar/gkt058

Article

MiR-10a* up-regulates coxsackievirus B3 biosynthesis by targeting the 3D-coding sequence

5 Feb 2013

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs that can posttranscriptionally regulate gene expression by targeting messenger RNAs. During miRNA biogenesis, the star strand (miRNA*) is generally degraded to a low level in the cells. However, certain miRNA* express abundantly and can be recruited into the silencing complex to regulate gene expression. Most miRNAs function as suppressive regulators on gene...

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