Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of the HGF/Met axis in mesothelioma.

Biochemical Society transactions - 15 Apr 2016

Thayaparan Thivyan, Spicer James F, Maher John

Abstract excerpt

Malignant mesothelioma is an asbestos-related cancer that occurs most commonly in the pleural space and is incurable. Increasing evidence suggests that aberrant receptor tyrosine kinase (RTK)-directed signalling plays a key role in the pathogenesis of this cancer. In the majority of mesotheliomas, up-regulated expression or signalling by Met, the receptor for hepatocyte growth factor (HGF) can be demonstrated....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HGF gene
Share to Hepatocyte Growth Factor
Share to Lung Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mesothelioma

Share to Mesothelioma, Malignant

Share to Mutation

Share to Proto-Oncogene Proteins c-met

Source

Identifiers

PMID: 27068941
DOI: 10.1042/BST20150252

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of the HGF/Met axis in mesothelioma.PMID 27068941Read ↗

HGF/c-MET Axis in Tumor Microenvironment and Metastasis FormationSemantic proximity Read ↗

Role of c-MET in upper aerodigestive malignancies--from biology to novel therapies.Semantic proximity Read ↗

Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunitiesSemantic proximity Read ↗

HGF/MET Signaling in Malignant Brain TumorsSemantic proximity Read ↗

Gene of the month: METSemantic proximity Read ↗

Targeting the hepatocyte growth factor/Met pathway in cancer.Semantic proximity Read ↗

MET: a critical player in tumorigenesis and therapeutic target.Semantic proximity Read ↗

The Met receptor tyrosine kinase: a key player in oncogenesis and drug resistance.Semantic proximity Read ↗

Targeting the c-Met Signaling Pathway in CancerSemantic proximity Read ↗

HGF/c-MET pathway in cancer: from molecular characterization to clinical evidenceSemantic proximity Read ↗

MET as a possible target for non-small-cell lung cancer.Semantic proximity Read ↗

Expression and mutational analysis of MET in human solid cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.