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Article

Splenic Ly6Chi monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient mice.

Basic research in cardiology - 1 Jul 2017

Tomczyk Mateusz, Kraszewska Izabela, Szade Krzysztof, Bukowska-Strakova Karolina, Meloni Marco, Jozkowicz Alicja, Dulak Jozef, Jazwa Agnieszka

Abstract excerpt

Heme oxygenase-1 (Hmox1) is a stress-inducible protein crucial in heme catabolism. The end products of its enzymatic activity possess anti-oxidative, anti-apoptotic and anti-inflammatory properties. Cardioprotective effects of Hmox1 were demonstrated in experimental models of myocardial infarction (MI). Nevertheless, its importance in timely resolution of post-ischemic inflammation remains incompletely...

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Identifiers

PMID: 28534119
DOI: 10.1007/s00395-017-0629-y
PMCID: PMC5440541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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