Article
Monocyte and macrophage contributions to cardiac remodeling.
Journal of molecular and cellular cardiology - 1 Apr 2016
Hulsmans Maarten, Sam Flora, Nahrendorf Matthias
Abstract excerpt
The mammalian heart contains a population of resident macrophages that expands in response to myocardial infarction and hemodynamic stress. This expansion occurs likely through both local macrophage proliferation and monocyte recruitment. Given the role of macrophages in tissue remodeling, their contribution to adaptive processes in the heart is conceivable but currently poorly understood. In this review, we...
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