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Plasmodium falciparum and Plasmodium vivax Demonstrate Contrasting Chloroquine Resistance Reversal Phenotypes

23 May 2017

Abstract excerpt

ABSTRACT High-grade chloroquine (CQ) resistance has emerged in both Plasmodium falciparum and P. vivax . The aim of the present study was to investigate the phenotypic differences of CQ resistance in both of these species and the ability of known CQ resistance reversal agents (CQRRAs) to alter CQ susceptibility. Between April 2015 and April 2016, the potential of verapamil (VP), mibefradil (MF), L703,606 (L7),...

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PMID: 28533239
DOI: 10.1128/aac.00355-17

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