Article
Therapeutic efficacy of chloroquine in Plasmodium vivax from areas with different epidemiological patterns in India and their Pvdhfr gene mutation pattern.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Sept 2006
Valecha Neena, Joshi Hema, Eapen Alex, Ravinderan John, Kumar Ashwani, Prajapati Surendra Kumar, Ringwald Pascal
Abstract excerpt
Among the four human malaria parasites, drug resistance occurs mainly in Plasmodium falciparum. However, there are some reports of chloroquine (CQ) resistance in P. vivax from different geographical regions. In India, approximately 50% of a total of 2 million cases of malaria reported annually are due to P. vivax. CQ is the drug of choice for treatment. Since few cases of treatment failure have been reported from...
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