Article
Ex vivo susceptibilities of Plasmodium vivax isolates from the China-Myanmar border to antimalarial drugs and association with polymorphisms in Pvmdr1 and Pvcrt-o genes.
PLoS neglected tropical diseases - 1 Jun 2020
Li Jiangyan, Zhang Jie, Li Qian, Hu Yue, Ruan Yonghua, Tao Zhiyong, Xia Hui, Qiao Jichen, Meng Lingwen, Zeng Weilin, Li Cuiying, He Xi, Zhao Luyi, Siddiqui Faiza A, Miao Jun, Yang Zhaoqing, Fang Qiang, Cui Liwang
Abstract excerpt
BACKGROUND: Vivax malaria is an important public health problem in the Greater Mekong Subregion (GMS), including the China-Myanmar border. Previous studies have found that Plasmodium vivax has decreased sensitivity to antimalarial drugs in some areas of the GMS, but the sensitivity of P. vivax to antimalarial drugs is unclear in the China-Myanmar border. Here, we investigate the drug sensitivity profile and...
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