Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii.

Abstract excerpt

Ribosome engineering has been widely utilized for strain improvement, especially for the activation of bacterial secondary metabolism. This study assessed ribosome engineering technology to modulate primary metabolism, taking vitamin B12 production as a representative example. The introduction into Propionibacterium shermanii of mutations conferring resistance to rifampicin, gentamicin, and erythromycin,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alkyl and Aryl Transferases
• Share to Erythromycin
• Share to Fermentation