Article
Engineering antibiotic producers to overcome the limitations of classical strain improvement programs.
Critical reviews in microbiology - 1 Jan 1996
Lal R, Khanna R, Kaur H, Khanna M, Dhingra N, Lal S, Gartemann K H, Eichenlaub R, Ghosh P K
Abstract excerpt
Improvement of the antibiotic yield of industrial strains is invariably the main target of industry-oriented research. The approaches used in the past were rational selection, extensive mutagenesis, and biochemical screening. These approaches have their limitations, which are likely to be overcome by the judicious application of recombinant DNA techniques. Efficient cloning vectors and transformation systems have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.