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Article

HFE genotype affects exosome phenotype in cancer.

Biochimica et biophysica acta. General subjects - 1 Aug 2017

Mrowczynski Oliver D, Madhankumar A B, Slagle-Webb Becky, Lee Sang Y, Zacharia Brad E, Connor James R

Abstract excerpt

Neuroblastoma is the third most common childhood cancer, and timely diagnosis and sensitive therapeutic monitoring remain major challenges. Tumor progression and recurrence is common with little understanding of mechanisms. A major recent focus in cancer biology is the impact of exosomes on metastatic behavior and the tumor microenvironment. Exosomes have been demonstrated to contribute to the oncogenic effect on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28527894
DOI: 10.1016/j.bbagen.2017.05.014

Genes

HFE

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