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Assessment of interleukin-1 gene cluster polymorphisms in lone atrial fibrillation: new insight into the role of inflammation in atrial fibrillation.

Pacing and clinical electrophysiology : PACE - 1 Oct 2013

Gungor Baris, Ekmekci Ahmet, Arman Ahmet, Ozcan Kazim S, Ucer Ekrem, Alper Ahmet T, Calik Nazmi, Yilmaz Hale, Tezel Tuna, Coker Ajda, Bolca Osman

Abstract excerpt

BACKGROUND: Systemic inflammation is accepted as one of the pathophysiological mechanisms of atrial fibrillation (AF). The role of inflammation has been shown previously. Interleukin (IL) system is the main modulator of the inflammatory responses and genetic polymorphisms of IL-1 cluster genes are associated with increased risk for inflammatory diseases. OBJECTIVES: To investigate the association between...

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PMID: 23713812
DOI: 10.1111/pace.12182

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