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Increased Vascular Endothelial Growth Factor Serum Level and the Role of +936C/T Gene Polymorphism in Chronic Obstructive Pulmonary Disease.

Medicina (Kaunas, Lithuania) - 10 Dec 2021

Chis Ana Florica, Râjnoveanu Ruxandra-Mioara, Man Milena Adina, Todea Doina Adina, Chis Bogdan Augustin, Stancu Bogdan, Arghir Ioan Anton, Alexescu Teodora Gabriela, Pop Carmen Monica

Abstract excerpt

Background and Objectives: Chronic obstructive pulmonary disease (COPD) represents a debilitating disease, with rising morbidity and mortality. Vascular endothelial growth factor (VEGF) plays a major role in angiogenesis, vascular permeability, and airway remodeling. The purpose of this study was to investigate the relationship between VEGF serum levels and VEGF +936 C/T gene polymorphism (rs3025039) with COPD,...

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Identifiers

PMID: 34946296
DOI: 10.3390/medicina57121351
PMCID: PMC8707840

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