Article
Association between -786TC polymorphism in the endothelial nitric oxide synthase gene and hypertension in the Tunisian population.
Experimental and molecular pathology - 1 Apr 2011
Jemaa Riadh, Kallel Amani, Sediri Yousra, Omar Souheil, Feki Moncef, Elasmi Monia, Haj-Taieb Samah, Sanhaji Haïfa, Kaabachi Naziha
Abstract excerpt
BACKGROUND: Nitric oxide (NO) is produced by endothelial cells and serves as a potent vasodilator. Several lines of evidence have shown that NO plays an important role in the regulation of blood pressure and regional blood flow. Recent genetic studies have shown an association between the -786TC polymorphism in the endothelial nitric oxide synthase gene (NOS3) and coronary artery diseases, but any possible...
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