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Article

APC hypermethylation for early diagnosis of colorectal cancer: a meta-analysis and literature review.

Oncotarget - 11 Jul 2017

Liang Tie-Jun, Wang Hong-Xu, Zheng Yan-Yan, Cao Ying-Qing, Wu Xiaoyu, Zhou Xin, Dong Shu-Xiao

Abstract excerpt

Adenomatous polyposis coli (APC) promoter hypermethylation has been frequently observed in colorectal cancer (CRC). The association between APC promoter methylation and clinicopathological significance in CRC is under investigation. We performed a meta-analysis to quantitatively evaluate the significance of APC methylation in CRC. The study included a total of 24 articles and 2025 CRC patients. The frequency of...

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Share to Adenomatous Polyposis Coli Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28515349
DOI: 10.18632/oncotarget.17576
PMCID: PMC5542282

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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