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Article

Prognostic role of IDH mutations in gliomas: a meta-analysis of 55 observational studies.

Oncotarget - 10 Jul 2015

Xia Liang, Wu Bin, Fu Zhiquan, Feng Fang, Qiao Enqi, Li Qinglin, Sun Caixing, Ge Minghua

Abstract excerpt

BACKGROUND: IDH (Isocitrate dehydrogenase) mutations occur frequently in gliomas, but their prognostic impact has not been fully assessed. We performed a meta-analysis of the association between IDH mutations and survival in gliomas. METHODS: Pubmed and EMBASE databases were searched for studies reporting IDH mutations (IHD1/2 and IDH1) and survival in gliomas. The primary outcome was overall survival (OS); the...

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Source

Open in PubMed Open full text

Identifiers

PMID: 26220714
DOI: 10.18632/oncotarget.4008
PMCID: PMC4627313

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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