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Article

Single-Strand Consensus Sequencing Reveals that HIV Type but not Subtype Significantly Impacts Viral Mutation Frequencies and Spectra.

Journal of molecular biology - 21 Jul 2017

Rawson Jonathan M O, Gohl Daryl M, Landman Sean R, Roth Megan E, Meissner Morgan E, Peterson Tara S, Hodges James S, Beckman Kenneth B, Mansky Louis M

Abstract excerpt

A long-standing question of human immunodeficiency virus (HIV) genetic variation and evolution has been whether differences exist in mutation rate and/or mutation spectra among HIV types (i.e., HIV-1 versus HIV-2) and among HIV groups (i.e., HIV-1 groups M-P and HIV-2 groups A-H) and HIV-1 Group M subtypes (i.e., subtypes A-D, F-H, and J-K). To address this, we developed a new single-strand consensus sequencing...

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Identifiers

PMID: 28502791
DOI: 10.1016/j.jmb.2017.05.010
PMCID: PMC5557043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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