Article
Social propinquity in rodents as measured by tube cooccupancy differs between inbred and outbred genotypes.
Proceedings of the National Academy of Sciences of the United States of America - 23 May 2017
Tuttle Alexander H, Tansley Shannon, Dossett Kimberly, Tohyama Sarasa, Khoutorsky Arkady, Maldonado-Bouchard Sioui, Stein Liane, Gerstein Lindsey, Crawhall-Duk Hayley, Pearl Rebecca, Sukosd Melissa, Leger Philip, Hardt Oliver M, Yachnin David, Austin Jean-Sebastien, Chan Claire M, Pooters Tine, Groves Isabelle, Martin Loren J, Sonenberg Nahum, Gkogkas Christos G, Mogil Jeffrey S
Abstract excerpt
Existing assays of social interaction are suboptimal, and none measures propinquity, the tendency of rodents to maintain close physical proximity. These assays are ubiquitously performed using inbred mouse strains and mutations placed on inbred genetic backgrounds. We developed the automatable tube cooccupancy test (TCOT) based on propinquity, the tendency of freely mobile rodents to maintain close physical...
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