Article
Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains.
Behavioural brain research - 10 Jan 2007
Moy Sheryl S, Nadler Jessica J, Young Nancy B, Perez Antonio, Holloway L Paige, Barbaro Ryan P, Barbaro Justin R, Wilson Lindsay M, Threadgill David W, Lauder Jean M, Magnuson Terry R, Crawley Jacqueline N
Abstract excerpt
Three defining clinical symptoms of autism are aberrant reciprocal social interactions, deficits in social communication, and repetitive behaviors, including motor stereotypies and insistence on sameness. We developed a set of behavioral tasks designed to model components of these core symptoms in mice. Male mice from 10 inbred strains were characterized in assays for sociability, preference for social novelty,...
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