Article
Deconstructing sociability, an autism-relevant phenotype, in mouse models.
Anatomical record (Hoboken, N.J. : 2007) - 1 Oct 2011
Fairless Andrew H, Shah Rhia Y, Guthrie Ashley J, Li Hongzhe, Brodkin Edward S
Abstract excerpt
Reduced sociability is a core feature of autism spectrum disorders (ASD) and is highly disabling, poorly understood, and treatment refractory. To elucidate the biological basis of reduced sociability, multiple laboratories are developing ASD-relevant mouse models in which sociability is commonly assessed using the Social Choice Test. However, various measurements included in that test sometimes support different...
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