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Article

Experiential modulation of social dominance in a SYNGAP1 rat model of Autism Spectrum Disorders.

The European journal of neuroscience - 1 Nov 2021

Harris Emma, Myers Honor, Saxena Kapil, Mitchell-Heggs Rufus, Kind Peter, Chattarji Shona, Morris Richard G M

Abstract excerpt

Advances in the understanding of developmental brain disorders such as autism spectrum disorders (ASDs) are being achieved through human neurogenetics such as, for example, identifying de novo mutations in SYNGAP1 as one relatively common cause of ASD. A recently developed rat line lacking the calcium/lipid binding (C2) and GTPase activation protein (GAP) domain may further help uncover the neurobiological basis...

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Identifiers

PMID: 34672048
DOI: 10.1111/ejn.15500
PMCID: PMC7614819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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