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Article

Modulation of social behavior and dominance status by chronic pain in mice.

Genes, brain, and behavior - 1 Jan 2019

Tansley Shannon N, Tuttle Alexander H, Wu Neil, Tohyama Sarasa, Dossett Kimberly, Gerstein Lindsay, Ham Boram, Austin Jean-Sebastien, Sotocinal Susana G, Mogil Jeffrey S

Abstract excerpt

The potential influence of pain on social behavior in laboratory animals has rarely been evaluated. Using a new assay of social behavior, the tube co-occupancy test (TCOT), we assess propinquity-the tendency to maintain close physical proximity-in mice exposed to pain using subcutaneous zymosan or spared nerve injury as noxious stimuli. Our previous experience with the TCOT showed that outbred mouse sibling dyads...

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PMID: 30125473
DOI: 10.1111/gbb.12514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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