Article
Down the Rabbit Hole of Single-Cell Genome Analysis.
Molecular cell - 4 May 2017
Eberwine James
Abstract excerpt
Chen et al. (2017) demonstrate whole-genome amplification of single-cell genomic DNA using linear nucleic acid amplification. This provides reliable single-nucleotide variation (SNV) detection across the single-cell genome, facilitating an understanding of cell-to-cell similarities and distinctions.
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