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Hypomethylation of CYP 2E1 and DUSP 22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients

29 Dec 2017

Abstract excerpt

OBJECTIVE: Epigenetic modifications have previously been associated with rheumatoid arthritis (RA). In this study, we aimed to determine whether differential DNA methylation in peripheral blood cell subpopulations is associated with any of 4 clinical outcomes among RA patients. METHODS: Peripheral blood samples were obtained from 63 patients in the University of California, San Francisco RA cohort (all satisfied...

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PMID: 29287311
DOI: 10.1002/art.40408

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