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Article

Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patients

7 Apr 2020

Abstract excerpt

Abstract Background The genetic risk associated with rheumatoid arthritis (RA) includes genes regulating DNA methylation, one of the hallmarks of epigenetic re-programing, as well as many T-cell genes, with a strong MHC association, pointing to immunogenetic mechanisms as disease triggers leading to chronicity. The aim of our study was to explore DNA methylation in early, drug-naïve RA patients, towards a better...

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Psoriasis: Treatment and Pathogenesis
Rheumatoid Arthritis Research and Therapies
T-cell and B-cell Immunology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32264938
DOI: 10.1186/s13148-020-00837-1

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