Article

Computational Assessment of the Regulation-Modulating Potential for Noncoding Variants

2019-10-28

Abstract excerpt

Large-scale genome-wide association and expression quantitative trait loci studies have identified multiple noncoding variants associated with genetic diseases via affecting gene expression. However, effectively and efficiently pinpointing causal variants remains a serious challenge. Here, we developed CARMEN, a novel algorithm to identify functional noncoding expression-modulating variants. Multiple evaluations d...

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Literature Corpus work: 278d0a81-0ff1-5826-96fd-4aeb4c6e2129
DOI: 10.1101/819409

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