Article
Competing endogenous RNA networks and gastric cancer.
World journal of gastroenterology - 7 Nov 2015
Guo Lei-Lei, Song Chun-Hua, Wang Peng, Dai Li-Ping, Zhang Jian-Ying, Wang Kai-Juan
Abstract excerpt
Recent studies have showed that RNAs regulate each other with microRNA (miRNA) response elements (MREs) and this mechanism is known as "competing endogenous RNA (ceRNA)" hypothesis. Long non-coding RNAs (lncRNAs) are supposed to play important roles in cancer. Compelling evidence suggests that lncRNAs can interact with miRNAs and regulate the expression of miRNAs as ceRNAs. Several lncRNAs such as H19, HOTAIR and...
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