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Article

Determination of VH Family Usage in B-Cell Malignancies via the BIOMED-2 IGH PCR Clonality Assay.

American journal of clinical pathology - 1 Jun 2017

McDonald Thomas J, Kuo Linus, Kuo Frank C

Abstract excerpt

OBJECTIVES: To determine whether V H family usage in B-cell lymphoproliferative disorders can be deduced from polymerase chain reaction (PCR) product-length information obtained through the BIOMED-2 (Invivoscribe, San Diego, CA) clonality assay. METHODS: We develop an algorithm that uses the sizing information of the BIOMED-2 immunoglobulin heavy chain (IGH) clonality assay to deduce V H family usage. PCR with...

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Share to B-Lymphocytes
Share to Clone Cells
Share to Gene Rearrangement, B-Lymphocyte, Heavy Chain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Heavy Chains

Share to Lymphoma, B-Cell

Share to Lymphoproliferative Disorders

Share to Molecular Diagnostic Techniques

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 28472420
DOI: 10.1093/ajcp/aqx007

Genes

IGH
NDN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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