Clonality testing of malignant lymphomas with the BIOMED-2 primers in a large cohort of 1969 primary and consultant biopsies.

doi:10.1016/j.prp.2013.05.004

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Article

Clonality testing of malignant lymphomas with the BIOMED-2 primers in a large cohort of 1969 primary and consultant biopsies.

Pathology, research and practice - 1 Aug 2013

Hartmann Sylvia, Helling Alexandra, Döring Claudia, Renné Christoph, Hansmann Martin-Leo

Abstract excerpt

The introduction of the BIOMED-2 primers allowed for reliable comparisons of clonality testing data of malignant lymphomas from different laboratories. This study undertook a retrospective analysis of a large cohort of cases; 1862 cases involved the immunoglobulin heavy chain locus (IGH VH-JH), and 1527 cases involved the T cell receptor gamma locus (TCRG). We confirmed previously published clonality rates in...

Topics

Biopsy
Clone Cells
DNA Primers
Diagnosis, Differential
Gene Rearrangement
Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
Genes, Immunoglobulin Heavy Chain
Genes, T-Cell Receptor gamma
Genetic Predisposition to Disease
Genetic Testing
Hodgkin Disease
Humans

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphoma

Lymphoma, B-Cell

Lymphoma, T-Cell

Phenotype

Polymerase Chain Reaction

Predictive Value of Tests

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Open in PubMed

Identifiers

PMID: 23827211
DOI: 10.1016/j.prp.2013.05.004

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