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Article

STOPGAP: a database for systematic target opportunity assessment by genetic association predictions.

Bioinformatics (Oxford, England) - 1 Sept 2017

Shen Judong, Song Kijoung, Slater Andrew J, Ferrero Enrico, Nelson Matthew R

Abstract excerpt

SUMMARY: We developed the STOPGAP (Systematic Target OPportunity assessment by Genetic Association Predictions) database, an extensive catalog of human genetic associations mapped to effector gene candidates. STOPGAP draws on a variety of publicly available GWAS associations, linkage disequilibrium (LD) measures, functional genomic and variant annotation sources. Algorithms were developed to merge the association...

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PMID: 28472345
DOI: 10.1093/bioinformatics/btx274

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