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Complement Component C3 Variant (R102G) and the Risk of Neovascular Age-Related Macular Degeneration in a Tunisian Population.

Klinische Monatsblatter fur Augenheilkunde - 1 Apr 2017

Habibi Imen, Sfar Imen, Kort Fedra, Bouraoui Rim, Chebil Ahmed, Limaiem Rim, Ayed Saloua, Ben Abdallah Taïeb, El Matri Leila, Gorgi Yousr

Abstract excerpt

Purpose To explore the association between the polymorphism (S/F) p.R102G in the complement component 3 (C3) gene and age-related macular degeneration (AMD) in a Tunisian population. Methods The molecular study was performed by polymerase chain reaction using sequence-specific primers (PCR-SSP) in 207 control subjects free of any eye disease (fundus normal) and 145 patients with exudative AMD. The CH50 activity...

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PMID: 28470643
DOI: 10.1055/s-0043-104419

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