Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complement C3 variant and the risk of age-related macular degeneration.

The New England journal of medicine - 9 Aug 2007

Yates John R W, Sepp Tiina, Matharu Baljinder K, Khan Jane C, Thurlby Deborah A, Shahid Humma, Clayton David G, Hayward Caroline, Morgan Joanne, Wright Alan F, Armbrecht Ana Maria, Dhillon Baljean, Deary Ian J, Redmond Elizabeth, Bird Alan C, Moore Anthony T

Abstract excerpt

BACKGROUND: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors. Complement activation is implicated in the pathogenesis. METHODS: We tested for an association between age-relat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Odds Ratio
Share to Protein Structure, Quaternary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Complement C3

Share to Complement C5

Share to Logistic Models

Share to Macular Degeneration

Source

Identifiers

PMID: 17634448
DOI: 10.1056/NEJMoa072618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17634448-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complement C3 variant and the risk of age-related macular degeneration.PMID 17634448Read ↗

Variation in complement factor 3 is associated with risk of age-related macular degeneration.Semantic proximity Read ↗

Complement component C3 and risk of age-related macular degeneration.Semantic proximity Read ↗

Systematic review and meta-analysis of the association between complement component 3 and age-related macular degeneration: a HuGE review and meta-analysis.Semantic proximity Read ↗

Association of polymorphisms in complement component 3 with age-related macular degeneration in an Iranian population.Semantic proximity Read ↗

Identification of a rare coding variant in complement 3 associated with age-related macular degeneration.Semantic proximity Read ↗

Nonsynonymous single nucleotide polymorphisms in the complement component 3 gene are associated with risk of age-related macular degeneration: a meta-analysis.Semantic proximity Read ↗

The complement system in age-related macular degeneration: A review of rare genetic variants and implications for personalized treatment.Semantic proximity Read ↗

A common complement C3 variant is associated with protection against wet age-related macular degeneration in a Japanese population.Semantic proximity Read ↗

Genetic Insights into Age-Related Macular DegenerationSemantic proximity Read ↗

Analysis of rare variants in the C3 gene in patients with age-related macular degeneration.Semantic proximity Read ↗

Update on the role of genetics in the onset of age-related macular degenerationSemantic proximity Read ↗

Association of c3 gene polymorphisms with neovascular age-related macular degeneration in a chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.