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Article

Multilevel regulation of an α-arrestin by glucose depletion controls hexose transporter endocytosis.

The Journal of cell biology - 5 Jun 2017

Hovsepian Junie, Defenouillère Quentin, Albanèse Véronique, Váchová Libuše, Garcia Camille, Palková Zdena, Léon Sébastien

Abstract excerpt

Nutrient availability controls the landscape of nutrient transporters present at the plasma membrane, notably by regulating their ubiquitylation and subsequent endocytosis. In yeast, this involves the Nedd4 ubiquitin ligase Rsp5 and arrestin-related trafficking adaptors (ARTs). ARTs are targeted by signaling pathways and warrant that cargo ubiquitylation and endocytosis appropriately respond to nutritional...

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Identifiers

PMID: 28468835
DOI: 10.1083/jcb.201610094
PMCID: PMC5461024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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