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Article

A calcineurin-dependent switch controls the trafficking function of α-arrestin Aly1/Art6.

The Journal of biological chemistry - 16 Aug 2013

O'Donnell Allyson F, Huang Laiqiang, Thorner Jeremy, Cyert Martha S

Abstract excerpt

Proper regulation of plasma membrane protein endocytosis by external stimuli is required for cell growth and survival. In yeast, excess levels of certain nutrients induce endocytosis of the cognate permeases to prevent toxic accumulation of metabolites. The α-arrestins, a family of trafficking adaptors, stimulate ubiquitin-dependent and clathrin-mediated endocytosis by interacting with both a client permease and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23824189
DOI: 10.1074/jbc.M113.478511
PMCID: PMC3745350

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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