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Article

Plasmodium falciparum histidine-rich protein 2 diversity in Ghana.

Malaria journal - 16 Jul 2020

Addai-Mensah Otchere, Dinko Bismarck, Noagbe Mark, Ameke Selassie Louis, Annani-Akollor Max Efui, Owiredu Eddie-Williams, Mensah Kofi, Tackie Richmond, Togbe Eliezer, Agyare-Kwabi Comfort, Gyasi Charles, Adu-Gyamfi Constance, Debrah Alexander Yaw

Abstract excerpt

BACKGROUND: In the absence of microscopy, Plasmodium falciparum histidine-rich proteins 2 (PfHRP2)-based rapid diagnostic tests (RDTs) are recommended for the diagnosis of falciparum malaria, particularly in endemic regions. However, genetic variability of the pfhrp2 gene threatens the usefulness of the test due to its impact on RDT sensitivity. This study aimed to investigate the diversity of pfhrp2 in malaria...

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Identifiers

PMID: 32678034
DOI: 10.1186/s12936-020-03328-z
PMCID: PMC7364488

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