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Genetic variability of Plasmodium falciparum histidine-rich proteins 2 and 3 in Central America

31 Jan 2019

Abstract excerpt

BACKGROUND: Malaria is an important disease in many tropical countries. Rapid diagnostic tests (RDTs) are valuable tools for diagnosing malaria in remote areas. The majority of RDTs used for the diagnosis of Plasmodium falciparum are based on the detection of the specific histidine-rich proteins (PfHRP2 and PfHRP3). During the last decade, the threat posed by the lack of expression of these antigens and the...

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PMID: 30704496
DOI: 10.1186/s12936-019-2668-3

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