Article
Genetic diversity of Plasmodium falciparum histidine-rich protein 2 in the China-Myanmar border area.
Acta tropica - 1 Dec 2015
Li Peipei, Xing Hua, Zhao Zhenjun, Yang Zhaoqing, Cao Yaming, Li Wenli, Yan Guiyun, Sattabongkot Jetsumon, Cui Liwang, Fan Qi
Abstract excerpt
Deletion of the Plasmodium falciparum histidine-rich protein 2 (pfhrp2) gene may affect the performance of PfHRP2-based rapid diagnostic tests (RDTs). Here we investigated the genetic diversity of the pfhrp2 gene in clinical parasite isolates collected in recent years from the China-Myanmar border area. Deletion of pfhrp2 has been identified in 4 out of 97 parasite isolates. Sequencing of the pfhrp2 exon2 from 67...
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