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Article

Serotonin Activated Hepatic Stellate Cells Contribute to Sex Disparity in Hepatocellular Carcinoma

17 Jan 2017

Abstract excerpt

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) occurs more frequently and aggressively in men than in women. Although sex hormones are believed to play a critical role in this disparity, the possible contribution of other factors largely is unknown. We aimed to investigate the role of serotonin on its contribution of sex discrepancy during HCC. METHODS: expression, differential rates of HCC in male and female...

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PMID: 28462385
DOI: 10.1016/j.jcmgh.2017.01.002

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