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Dopamine-induced SULT1A3/4 promotes EMT and cancer stemness in hepatocellular carcinoma

1 Oct 2017

Abstract excerpt

Hepatocellular carcinoma has the second highest incidence rate among malignant cancers in China. Hepatocellular carcinoma development is complex because of the metabolism disequilibrium involving SULT1A3/4, a predominant sulfotransferase that metabolizes sulfonic xenobiotics and endogenous catecholamines. However, the correlation between SULT1A3/4 and hepatocellular carcinoma progression is unclear. By utilizing...

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PMID: 29025375
DOI: 10.1177/1010428317719272

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