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Article

Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.

American journal of physiology. Gastrointestinal and liver physiology - 1 Feb 2011

Omenetti Alessia, Yang Liu, Gainetdinov Raul R, Guy Cynthia D, Choi Steve S, Chen Wei, Caron Marc G, Diehl Anna Mae

Abstract excerpt

Paracrine signaling between cholangiocytes and stromal cells regulates biliary remodeling. Cholangiocytes have neuroepithelial characteristics and serotonin receptor agonists inhibit their growth, but whether they are capable of serotonin biosynthesis is unknown. We hypothesized that cholangiocyt...

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Identifiers

PMID: 21071507
DOI: 10.1152/ajpgi.00368.2010
PMCID: PMC3043647

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21071507-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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